Karl: In the first film, he reforms and becomes a protagonist. In the final film, falls to his death in a waterfall before he could kill the crocodiles.
Chauncey: In the first film, he reforms and becomes a protagonist. In the final film, he falls to his death with his owner in a waterfall.
Eugene Clark: Escapes the purple gloop, mourns the loss of his younger brother, sadly walks away, reforms and becomes a protagonist.
Dernard: Punished by his mom Cynthia (2nd film). Gets scared by the Enchantress, launched to Bermuda by Bernard and the Guardians of Brendam and eaten alive by a monster along with Pepe (4th film).
Carlos: Gets crushed by the crumbled volcano and exploded by the volcano's lava
Carlos' henchcards: Get killed with their boss
Prince John: Gets crushed by a boulder in the final scene
The Bears: Get arrested by the police in the final scene
Henry J. Smek: Gets hit by Toto with a golf ball near the film's final battle, gets exiled from Brendam by Bernard using a portal making shock collar.
Palpatine: Gets trapped by Bernard in logs as he rescues his friends.
Fearless Leader, Boris Badenov & Natasha Fatale: Get exiled from the island by Bernard as he saves his fellow guardians.
Ernest of the Cross: Gets defeated by Bernard and his friends's trap and it comes to an end with Toto and Joe's Prank-Me-Not Poncho that floats him to the moon.
Pepe: Gets attacked by Bernard with the Guardians' help but reforms and helps Bernard defeat Ernest. At the end, he dances with his friends.
Count Roderick Von Zipper: Gets defeated by Bernard during the Count's final chase and melts.
Vlad Vladikoff: Get beaten up by Bernard and later reform and dance at the finale party.
Ivan the Terrible, Napoleon Bonaparte, and Al Capone: Get scared by Joe and fall off the cliff.
Kyle: Cries while watching Ernest fly away, reforms and becomes a protagonist and the new leader of the Settlers. He and Ernest are the only two characters paticipating at the finale dance party of the film.
Lawrence "Larry" Quinn: Gets caged and gets tormented by Victor at the end of the film.
The Settlers: Reform and return to Ernest, Inc.
The Intergalactic Council of Superior Beings: Get killed by the Guardians, accompanied by fireworks.